House

Dr. Gregory House e sua equipe só atendem casos médicos depois que todos os outros não conseguem diagnosticar um paciente. Uma professora de jardim de infância começa a falar coisas sem sentido e desmaia na frente da turma. O que parece ser um possível tumor cerebral não responde ao tratamento e fornece muito mais perguntas do que respostas para House e sua equipe enquanto eles se envolvem em uma abordagem arriscada de tentativa e erro para o caso dela. Quando a jovem professora recusa quaisquer variações adicionais de tratamento e a sua vida começa a desaparecer, House deve agir contra o seu código de conduta e fazer uma visita pessoal à sua paciente para convencê-la a confiar nele uma última vez.

Quando um adolescente jogador de lacrosse é acometido de uma doença cerebral não identificável, o Dr. House e a equipe se esforçam para dar respostas a seus pais. Chase dá a má notícia de que o garoto tem esclerose múltipla, mas as alucinações de terror noturno do garoto refutam o diagnóstico e mandam House e sua equipe de volta à estaca zero. À medida que a saúde do menino se deteriora, a aposta paralela de House na paternidade do paciente enfurece a Dra. Cuddy e os pais do adolescente, mas pode valer a pena. 

Um estudante universitário desmaia após sexo turbulento com sua namorada. Enquanto House e sua equipe tentam determinar a causa, a condição do aluno continua a piorar e seus sintomas se multiplicam, complicando o diagnóstico.

House exaspera sua chefe, Dra. Lisa Cuddy, quando sugere que dois bebês recém-nascidos doentes em um hospital resultam em uma epidemia de um vírus em propagação. Ainda mais assustador é que ele pode estar certo quando mais quatro bebés adoecem, a maternidade fecha e os médicos discutem os tratamentos. House e sua equipe devem tomar decisões que podem comprometer a vida dos bebês.

Quando uma freira chega à clínica com braços inchados, erupções cutâneas e sangramento nas palmas das mãos, o diagnóstico da Dra. House é uma alergia grave, não estigmas, como ela acredita. House dá a ela um anti-histamínico que parece desencadear um ataque alérgico. No entanto, quando a freira fica com taquicardia por causa da epinefrina que House lhe dá para tratar, Cuddy conclui que ele lhe deu dez vezes a dose apropriada. Quando House insiste que lhe deu a dose adequada, Cuddy lhe dá 24 horas para provar que a freira tem outra condição antes de ligar para os advogados de negligência médica. Embora House finalmente se justifique, a resposta não ajuda o paciente. À medida que sua condição piora, suas irmãs oram por ela enquanto House e sua equipe trabalham para descobrir a causa de sua doença. House se pergunta se ele diagnosticou mal a situação dela, sem perceber que o passado dela está voltando para assombrá-la.

Ao se esquivar de Cuddy na sala de emergência, House encontra o filho de uma mulher esquizofrênica com diagnóstico de alcoolismo. Intrigado com a esquizofrenia dela e com o fato de ela ter trombose venosa profunda mortal, uma condição que ela é muito jovem para ter, ele pega o caso dela e encontra vários problemas. No entanto, quando a paciente faz algo inesperado, House começa a se perguntar se ela é realmente doente mental.

Depois que Ed Snow descobre que sua esposa Elyse dorme constantemente por vários dias, ela é internada no hospital. Dr. Cameron está muito interessado no caso. Tanto que o interesse dela convence House a aceitar o caso. Os médicos ficam intrigados com os sintomas dela, considerando tudo, desde tumores até câncer de mama e febre do coelho. Quando todos os tratamentos falham, House conclui que ela tem a doença do sono africana, contraída através de relações sexuais. No entanto, nem Elyse nem Ed alguma vez estiveram em África. Nenhum dos dois admitirá ter um caso. Ela morrerá sem o tratamento adequado.

Quando um estudante do ensino médio é vítima de um envenenamento misterioso, mas letal, House e sua equipe investigam o que está matando o adolescente. De repente, um segundo aluno não aparentado é admitido com sintomas idênticos. Com a vida dos meninos em jogo, House e a equipe precisam ligar os pontos rapidamente. Enquanto isso, uma paciente de 82 anos se apaixona por House enquanto ele a ajuda a descobrir a base de seu fascínio renovado por seus sentimentos sexuais.

O lendário músico de jazz John Henry Giles dá entrada no Princeton Plainsboro Teaching Hospital acreditando que está morrendo de ELA e assina um DNR para evitar uma morte lenta. House discorda do diagnóstico e vai contra a vontade de todos ao violar o DNR para salvar a vida de Giles. A decisão leva House ao tribunal, leva Foreman a considerar aceitar outro emprego e resulta no agravamento da paralisia de Giles. Mas quando o paciente inexplicavelmente começa a melhorar, a equipe precisa desvendar o mistério ao contrário e descobrir por que sua condição está melhorando.

Foreman acredita que uma sem-teto que não coopera está fingindo ter convulsões para conseguir um vale-refeição grátis no hospital universitário. Mas a falta de moradia dela toca pessoalmente o Dr. Wilson, e ele fica determinado a evitar que ela caia nas rachaduras. O agravamento dos sintomas dela prova ser um mistério complexo para House e sua equipe, mas o mistério de sua identidade e histórico médico pode conter as respostas para salvar sua vida. No momento em que a equipe suspeita que ela tenha meningite contagiosa, a mulher desaparece, apenas para ser eletrocutada pela polícia, que a traz de volta. Mas House deduz que o taser pode ter provado mais um diagnóstico, com resultados terríveis. Enquanto isso, House tem um público formado por dois estudantes de medicina que estão aprendendo a fazer estudos de caso.

House precisa determinar por que um jovem paciente teve hemorragia interna após um acidente de carro. Nesse ínterim, ele aceita o desafio de Cuddy de parar de tomar Vicodin por uma semana em troca de não trabalhar na clínica por um mês. Mas a equipe acredita que os sintomas de abstinência de House afetam seu julgamento ao analisar a inexplicável perda de sangue do jovem.

Um braço gravemente quebrado revela um caso bizarro de perda óssea e encerra os planos de retorno do arremessador da liga principal Hank Wiggen. House suspeita que Hank está mentindo sobre o uso de esteróides à medida que sua condição piora. Quando os rins de Hank começam a falhar, sua esposa se oferece para doar os dela, mas ela teria que abortar a gravidez precoce. Forçado a uma solução impossível e admitindo o fracasso como viciado, Hank tenta tirar a própria vida. House e sua equipe devem isolar e resolver o problema em breve se a vida e a carreira deste arremessador puderem ser salvas. Enquanto isso, Foreman sai com um representante farmacêutico, e House fica com dois ingressos e vai a um "encontro" com Cameron para um comício de monster truck.

A 12-year-old boy believes he's cursed after a Ouija board tells him he's going to die. His father, a major financial supporter of the hospital, makes escalating demands of House and the team as they try to diagnose the boy's pneumonia-like symptoms and incongruous rash. Meanwhile, Chase's estranged father, a renowned doctor from Australia, visits, and House invites him to sit in, much to Chase's discomfort. When House diagnoses the boy's illness, the young patient is forced to face the idea that his father may not be everything he believes.

O empresário bilionário Edward Vogler gasta US$ 100 milhões no Hospital Universitário Princeton-Plainsboro e se torna o novo presidente do conselho. Como empresário, Vogler pretende transformar a clínica em um local lucrativo para seu novo empreendimento de biotecnologia e planeja eliminar os serviços financeiramente desgastantes do Dr. Enquanto isso, uma empresária que tem tudo – vida perfeita, corpo perfeito, emprego perfeito – fica inexplicavelmente paralisada. Quando ele descobre o segredo dela, House deve arriscar sua carreira e licença médica para conseguir um transplante necessário para ela.

Pouco antes do mafioso Joey Arnello desabafar no tribunal federal e entrar na proteção a testemunhas, ele desmaia. Ele está fingindo? Uma ordem judicial instrui House a descobrir – e rápido. House e sua equipe lutam para diagnosticar e curar Joey enquanto o irmão de Joey, Bill, tenta desacelerar as coisas e impedir Joey de testemunhar. Enquanto isso, Cuddy luta para convencer Vogler de que House é uma parte essencial do hospital.

House deve demitir um de seus médicos por insistência de Vogler e os deixa pensando sobre isso enquanto lidam com um caso. House e sua equipe culpam uma reação adversa às pílulas dietéticas depois que uma menina obesa de 10 anos teve um ataque cardíaco, mas acabam descobrindo uma fonte muito mais mortal para sua doença. House examina uma mulher que não aceita a cirurgia para um tumor de 30 libras porque deseja permanecer acima do peso.

At a high-level campaign fundraiser, up-and-coming Senator Tom Wright becomes violently ill. Vogler pushes House to take Wright's case and dangles a new incentive in front of him: deliver a speech on behalf of Vogler's pharmaceutical company and save his whole team without firing one. House examines the senator finding that the symptoms point toward AIDS, a condition that would squash his career and presidential aspirations. But House refuses to settle for the easy answer. And House ends up giving the speech, but it doesn't go quite as Vogler planned.

Enquanto House e sua equipe lutam para descobrir o que está causando a disfunção cerebral e renal em uma mulher grávida, Vogler está em pé de guerra para fazer com que House seja demitido após o discurso farmacêutico de House. House determina a doença, mas a mulher e o marido enfrentam uma escolha emocional e dolorosa entre ela ou o filho ainda não nascido. Vogler pede uma votação do Conselho de Administração para destituir House, mas quando Wilson se recusa a tornar a votação unânime, Vogler ameaça pegar seu dinheiro se o Conselho não destituir Wilson. Finalmente, Cuddy deve se posicionar contra Vogler.

Durante um surto de meningite que sobrecarrega os recursos e a equipe do Hospital Universitário de Princeton-Plainsboro, House destaca um paciente de 12 anos cujos sintomas são semelhantes, mas não exatamente adequados para a doença. House, Foreman e Chase devem inventar maneiras e locais engenhosos para tratar a delicada condição da garota no meio do caos e fazer uma descoberta inesperada. Enquanto isso, House pede a Cameron que volte ao trabalho, mas ela tem um requisito que ele talvez não consiga cumprir.

House apparently scares a meek clinic patient into having a stroke. The team must deal with the patient's odd lifestyle, overbearing "friend," and reluctant parents to stop the strokes and try to save his life. But the major topic of discussion is House's imminent date with Cameron, which is her condition for accepting House's rehire offer. Meanwhile, Wilson, Cuddy, and the team offer House and Cameron advice while laying odds on the outcome.

A ex-namorada de House e ex-assessora jurídica do hospital, Stacy Warner, retorna não para estar com House, mas para obter sua ajuda para diagnosticar seu marido doente. Enquanto House decide se aceita ou não o caso, Cuddy o obriga a substituir um professor doente e dar uma palestra para uma turma de estudantes de medicina. Ao entrelaçar as histórias de três pacientes que apresentam sintomas semelhantes, House dá uma lição que os alunos jamais esquecerão.

House insiste que pode lidar com as coisas quando Stacy, a mulher que ele amou, pede que ele diagnostique seu marido, Mark. Mas apesar dos testes de Mark terem voltado ao normal, seus sintomas crescentes indicam que ele está morrendo. Enquanto House luta com o mistério e exige cada vez mais de sua equipe, Wilson se preocupa com o bem-estar emocional de House. Trabalhando para salvar Mark, House não pode deixar de pensar que seus sentimentos por Stacy podem ter reacendido. Cuddy considera contratar Stacy se House concordar; ele faz.

When Death Row inmate Clarence mysteriously and suddenly collapses after hallucinating, House jumps at the chance to take the case for its difficulty and because it's "cool" over Cuddy and Foreman's objections. Dr. Cameron refuses to treat the patient in protest and feels they should treat a cancer patient because she's more deserving, raising the question: is one life more important than another? Also, House must now work closely with Stacy.

Andie, uma paciente terminal de câncer de 9 anos, sofreu um episódio alucinógeno e foi internada no hospital. Wilson convence House a aceitar o caso, mas ele e sua equipe lutam para diagnosticar o que causou a alucinação. A jovem lida tão bem com sua doença que House se pergunta se ela é realmente tão corajosa ou se é um sintoma médico.

When Cuddy's handyman Alfredo, a young Latino and the sole provider for his family, falls from her roof and develops strange darkened pinkies, Cuddy joins the team in trying to figure out what's wrong with him.

Sebastian Charles, renomado médico e chefe de uma organização internacional para combater a propagação da tuberculose entre os pobres na África, é levado às pressas para o Hospital Universitário de Princeton Plainsboro após desmaiar, ele imediatamente determina que todos os sintomas são de tuberculose. Dr. House tem uma opinião diferente e solicita exames adicionais para ajudar a determinar a causa de sua doença.

A graduating Princeton student suffers a seizure from internal shocks while partying at a frat house and is rushed to Princeton Plainsboro Hospital. With his father Ken at his bedside, it becomes apparent the two haven't been truthful about their lives with each other. Their trust issues prevent the medical team from getting the necessary information to diagnose and treat Carnell's illness. Also, House's parents drop by to see their son.

When a famous professional cyclist is brought in after collapsing during a race, House doesn't want to treat him because he thinks he's lying about doing drugs. But when the patient is forthcoming about taking all sorts of performance enhancers and blood-doping drugs, House is definitely intrigued.

Kalvin, a gay man with full-blown AIDS, confronts House in front of his home, demands that House figure out what's causing his illness - besides HIV or AIDS - and collapses at his feet, going into shock. When House discovers the man's father is suffering from symptoms of his own, he must determine any connection to save both their lives. Meanwhile, Cameron faces a potentially life-threatening disease of her own.

Kayla, the mother of two young girls, doubles over with stomach pain during her children's talent show and is rushed to Princeton-Plainsboro Teaching Hospital. Six months later, Stacy counsels Dr. Chase and Dr. House in preparation for a disciplinary hearing to determine if either Chase or House made a mistake that ultimately led to Kayla's death and her family's subsequent lawsuit. She soon realizes Chase is holding something back.

Off-track betting gambler Anica collapses in front of House while both follow horse races at the site. Confused by her symptoms and what he witnessed after she collapsed, he instructs medics to take her to Princeton Plainsboro and takes her case. With Foreman temporarily House's supervisor, the team must figure out if Anica, who cried wolf many times, is really ill. 

O jornalista Fletcher Stone desmaia na festa de aposentadoria de seu editor e bate a cabeça na mesa. Suas frases ficam distorcidas e incoerentes quando ele recupera a consciência, então ele é levado às pressas para o Hospital Universitário de Princeton Plainsboro. House e Stacy estão fora da cidade defendendo as contas do Medicaid de House e mais tarde ficam presos em um aeroporto devido ao mau tempo. Então, a equipe luta para resolver o caso sozinha. 

Margo, a young housewife on fertility medication, is brought to Princeton Plainsboro Hospital when her inexplicable muscle flailing causes her to crash her car. House and Stacy try to resolve their relationship issues once and for all. Cameron refuses to take her HIV test, wary of the results. 

House and his team have a difficult challenge when a teenage boy enters the hospital severely burned with unusual blood-test results. How can you diagnose a burn victim when you cannot use standard testing methods? House makes himself the guinea pig in his own unofficial tests of a new drug designed to treat migraines to prove a former medical school colleague is wrong about the drug.

House and his team work to treat a teenage supermodel for heroin addiction and, in the process, uncovers a startling secret about the girl.

When Henry experiences a seizure but is not aware of it while it's happening, House takes on the case. The team's differential diagnosis points to a bacterial infection, but Henry suffers a heart attack before the treatment for his infection can work, prompting the need for a heart transplant. Then, the team races to diagnose a dead woman's illness so they can harvest her heart to save their living patient.

House and his team take on a new patient, Bob, who comes to Princeton Plainsboro Teaching Hospital after suffering from a breathing attack while role-playing in the bedroom with his wife. The symptoms point to heavy metal poisoning, but the tests do not. House believes a woman is trying to kill her husband and tries to find the proof to confirm his suspicions. When Wilson moves in with House after separating from his wife, he learns Wilson is a great cook.

6 months after a teenage girl crushes her chest in a car accident and receives a heart transplant she goes into anaphylactic shock in her clean room bedroom after her boyfriend visits.

It's poker night at Princeton Plainsboro when the hospital hosts an oncology benefit. A 6-year-old boy is brought in exhibiting symptoms that aren't too unusual; however, when House learns of additional specifics, he jumps on the case right away.

A young woman, Hannah, hasn't been able to sleep for 10 days. She's brought in after she downed an entire bottle of sleeping pills and still didn't fall asleep. Meanwhile, Cameron accuses Foreman of stealing a medical journal article she wrote, which Foreman denies.

When 15-year-old faith healer, Boyd, is admitted and claims he can talk to God, House takes the case. House thinks the kid is a clever con until the boy touches one of Wilson's cancer patients and causes her cancer to go into remission.

When a police officer with a gunshot wound to the head and uncontrollable laughter is admitted, House and the team are baffled. When Foreman begins showing the same bizarre symptoms, they race to determine the cause of the illness before Foreman's condition takes the same path.

Foreman continues to experience the same dire progression of symptoms as the dead police officer: blindness, muscle contractions, and excruciating pain. When he realizes he may be facing imminent death, he calls his father and tries to make amends; his father comes to his son's side. As it comes down to a race against time, House believes the solution to the illness is in the police officer's apartment. House tries radical procedures to save Foreman's life.

When young mother, Kara, has a seizure while bathing her child, it causes the near drowning of her newborn son. Unable to determine the cause of Kara's seizures, House and the team race to find what's wrong with her while simultaneously trying to bring her infant back to life.

A 16-year-old Hurricane Katrina victim suffering from hallucinations due to the tragedy is brought to House by his former bandmate, Crandall, who recently found out the girl is his daughter. Although House fears his friend is being scammed, he takes the case. As he works his way through the girl's lies so he can diagnose and treat her, he's forced to tell a few lies of his own. Also, Cuddy looks for a sperm donor.

As House and his team diagnose Vince, a man with a giant, swollen tongue, a disgruntled former patient Jack Moriarty walks into House's office and shoots him. House continues treating his patient from his ICU hospital bed with Jack, who hospital security shot and hand-cuffed to his bed, as his roommate. When the after-effects of the shooting begin to impact House, he starts to question his ability to diagnose correctly. As his patient's body deteriorates, House struggles through his self-doubt and must trust his team to find a way to solve the case.

House has recovered from multiple gunshot wounds and is back at work, taking on two cases simultaneously: Richard, paralyzed after brain cancer surgery eight years ago, who drove himself on his motorized wheelchair headfirst into a swimming pool; and Caren, a young woman paralyzed from the neck down after a yoga session.

House's ego has taken quite a blow because he failed to diagnose his last case, and it's affecting him physically. He is obviously in pain again, although he continues to deny it. House's new case is 7-year-old Clancy, a product of in-vitro fertilization, who's been admitted to the hospital with rectal bleeding and proclamations of being tortured by aliens.

The ketamine has worn off and House is back to using his cane and doesn't want to talk about it. His new patient is Ezra Powell, a renowned pioneer in the field of medical research, who collapsed in his lab.

House takes the case of Adam, a 10-year-old severely autistic boy who screams loudly for no apparent reason, at least not a reason his three previous doctors could diagnose. The team wonders why House is taking the case - the boy's not sick; his symptoms seem to be a product of his autism.

House takes on the case of 20-year-old female patient Tracy Dawson, who is rushed to Princeton Plainsboro Teaching Hospital with breathing difficulties and unexplained intense abdominal pain after she and her husband, Jeremy, are victims of a robbery. Meanwhile, House and clinic patient Michael Tritter have a touchy altercation, leaving Tritter appalled and furious at the way House treated him.

A 600-pound man, George Hagel, is admitted to the hospital after he is found in his apartment in a coma. While they conduct the necessary tests, the team runs into several obstacles due to the sheer mass of the patient.

Kyle comes to the hospital regularly to visit his father, Gabe, who has been in a coma for 10 years. Noticing something "off" about Kyle, House conducts a mini-experiment that leaves the boy unconscious. When symptoms point to a possible genetic condition, House and his team must glean a family history from Kyle's only living relative - his comatose father.

House's newest patient is 18-year-old Jack, brought to the hospital after experiencing a heart attack and massive vomiting. Barely an adult himself, Jack has been the parent to his younger brother and sister since their parents died. Meanwhile, in an attempt to extract a confession, Tritter makes it almost impossible for Wilson to practice medicine.

House and the team take on the case of Alice, a young girl with pancreatitis. Since her divorced parents can't agree on how to proceed with her treatment and won't let House bully them into making a decision, House's only option is to take them to court and let a judge rule on the matter.

It's Christmas at Princeton-Plainsboro and Wilson has a present for House - he and Detective Tritter have struck a deal and House has three days to accept it. Meanwhile House's new patient is a little person with an interesting puzzle to solve.

House is forced to respond in court to the criminal charges against him regarding illegal possession of narcotics, and the judge sets a date for a preliminary hearing. Meanwhile, the case of Derek Hoyt, a firefighter suffering from extreme body temperatures and disorientation, leads the team to believe their patient is suffering from an extreme hormone imbalance.

At the clinic, House encounters patient Eve, who has tested positive for an STD and admits she's very recently been raped. Knowing he can't do anything more for Eve medically, House refers her to a psychiatrist, but she refuses to talk to the doctor and will only be treated by House.

16-year-old Stevie Lipa is admitted to Princeton Plainsboro Teaching Hospital with a serious respiratory condition and internal bleeding. Oddities of his case land him under House and the team's care, but at the moment, House is irritated to learn that new hospital researcher Dr. Julie Whitmer has been assigned his handicapped parking spot by the hospital entrance.

It's Valentine's Day at Princeton-Plainsboro and the ER is short-staffed due to a snowstorm. House encounters Foreman's latest patient, Hannah, who has sustained injuries from a car accident with her mother, Abby. House notices that despite her best efforts to act injured, Hannah is not feeling a bit of pain.

Patrick Obyedkov, a 35-year-old musical savant, is in the middle of playing a piano concert when he suffers a painful involuntary muscle contraction in his left hand. After Patrick is admitted to Princeton-Plainsboro Hospital with a rare movement disorder, his case attracts the attention of Dr. House.

House is bewildered yet intrigued when he meets his newest patient, John Kelley, an ex-Marine who had saved House's life in a very realistic dream the night before.

A famous, 42-year-old, pregnant photographer, Emma Sloan, is brought to the hospital after suffering a stroke in the middle of a high-profile photo shoot with Tyson Ritter. Although Emma's condition initially stabilizes, her health takes a turn for the worse when her kidneys inexplicably fail.

On the plane home from a conference in Singapore, House and Cuddy encounter a potentially deadly infection when a man beside House becomes violently ill. Back at Princeton-Plainsboro, Wilson leads the team when they encounter Fran, a middle-aged woman who collapses at her home and soon goes into seizures.

When 6-year-old Lucy collapses at daycare, the team is mystified when, far too young, she starts developing symptoms of puberty. Tensions between Chase and Cameron lead House to intentionally assign them to the same tasks, including investigating the young girl's home.

The team takes on the case of Lupe, a young female scam artist who passes out while working a card-playing scheme on the streets.

Wilson prepares his 14-year-old leukemia patient, Nick, for a last-resort bone marrow transplant from his younger brother, Matty. With Nick's immune system completely wiped out from chemotherapy, Wilson is extremely cautious about keeping him healthy before the transplant. However, when Matty sneezes during a pre-op visit to his brother, Wilson knows that Matty is not healthy enough to donate.

Addie, a 19-year-old college student, is admitted to Princeton Plainsboro after coughing up a mouthful of blood during karate class. Before treating the patient, Foreman unapologetically informs the rest of the team that he is resigning, but will not say why.

Obnoxious 16-year-old chess prodigy Nate is admitted to Princeton-Plainsboro suffering from intense head pain that came on after he attacked his opponent during a speed chess tournament.

Cuban couple Esteban and his sick wife, Marina Hernandez, are pulled from the ocean during a dangerous rescue en route to the U.S. on a mission to reach Dr. House. Her detailed medical records from Cuba were lost during the rescue, so the team runs a series of tests to determine the extent of her heart condition. But when she gets worse, House wonders if someone on his staff made a mistake. Meanwhile, Foreman prepares to leave, and his departure shakes up the entire team with House firing Chase and Cameron resigning. 

With his diagnostic team gone, House tries to diagnose Megan, a young woman who survived an office building collapse. Due to her injuries, Megan's only form of communication is blinking. With her condition worsening, Cuddy puts pressure on House to hire a new team, but instead, he attempts a differential diagnosis with help from the janitor. Wilson resorts to desperate measures by kidnapping House's guitar.

House has relented to interviewing potential team members, but he's doing it his way. He called in all 40 applicants for the open three positions on his team and puts them to the test in a Darwinian trial period. As he drills the fellows and arbitrarily fires some along the way, an Air Force fighter pilot named Greta asks him to secretly treat her. She is a candidate for NASA's astronaut training program. House sets the applicants against one another to help treat the pilot with an unusual neurological disorder.

The final 10 fellowship candidates compete ferociously when House splits them into two teams by gender. They are assigned to diagnose and treat a wheelchair-bound man with muscular atrophy who is slowly suffocating.

When a 20-year-old funeral home cosmetician, Irene, has a massive seizure, she hallucinates the cadavers in the funeral home have come to life, House and the remaining seven fellowship candidates must figure out why.

The team takes on the case of a man who collapsed while being mugged. When the man complains of new symptoms that do not fit his initial admission profile, the team suspects he is a hypochondriac. As Mr. X continues to fall ill with symptoms unrelated to his neurological disorder, Foreman and the remaining six fellows are assigned to keep watch, and are bemused as they see their own behavioral idiosyncrasies reflected through him.

House is recruited by the CIA to help diagnose a deathly ill agent with an unknown illness. Meanwhile, Foreman faces resistance from the remaining six fellowship candidates when they question his judgment and argue over the diagnosis of a female drag car racer who passed out after a race.

A documentary film crew chronicles a teenager with a major facial deformity who opts to undergo a dramatic reconstructive procedure. When the patient suffers a heart attack just before the surgery, House and the fellowship candidates must determine the cause since the surgery cannot proceed until the patient's cardiac condition is diagnosed. The film crew and the candidates, following around House, distract him.  

House encounters a magician whose heart failed while performing an underwater escape act, nearly drowning. While the remaining fellowship candidates work to diagnose the illusionist, House is determined to prove that he's a scam artist faking his ailments to cover up his own incompetence. Meanwhile, House pits the fellows against each other in his version of an immunity challenge.

When Cuddy puts the pressure on House to choose the final members of his team, House deliberately assigns the candidates to a particularly challenging case - an uncooperative, over-the-hill former punk rock star with a history of drug abuse and civil disobedience.

House and the team treat a woman who suffers from a sudden paralysis of the hands that causes an injury to her daughter while she's spotting her at an indoor rock-climbing wall. As House probes the woman and her injured daughter for any leads as to what might be causing her condition, House is convinced that the woman is withholding information.

When Dr. Cate Milton, a psychiatrist trapped at the South Pole and the research station's only doctor, becomes ill in the middle of her assignment, she and Dr. House are thrust into a long-distance relationship of sorts. Unable to get Cate out or any additional medical supplies to the South Pole station, House and his team must resort to treating her via webcam.

House and the team encounter a woman admitted to Princeton-Plainsboro after she collapsed at her wedding. Her test results come up negative for a variety of common diseases, which leads the team to suspect foul play. Meanwhile, House is preoccupied by Wilson's newly-outed relationship with a woman whose personality is remarkably similar to House's.

House suspects an emergency room patient has a bigger problem then the ER initially diagnosed based on the fact that the patient is too nice. A skeptical House questions the patient's sunny disposition as the team tries to get to the bottom of his illness. Meanwhile, House and Amber are at odds about how much time they each get to spend with Wilson, and Cuddy demands House give his team performance reviews.

House is convinced one of the actors on his favorite soap opera "Prescription Passion" has a serious medical condition after observing his symptoms on television. House decides to intervene and take matters into his own hands.

House finds himself dazed, confused and covered in blood after surviving a bus accident that left dozens seriously injured. Unable to clearly recall the events leading up to the crash due to his head injuries, House becomes convinced through his flashbacks that a fellow bus passenger was exhibiting signs of a deadly illness prior to the crash.

House remains inhibited by injuries sustained from a bus accident that has also left a victim rapidly deteriorating from a mysterious condition. Clues inside House's head hold the key to a patient's condition, and House's friendship with Wilson is tested beyond limits as murky memories from the bus accident the night before threaten to change their lives forever.

Eight weeks after the death of his girlfriend, Amber, Wilson is still mourning her death, and his relationship with his best friend House is shattered. Needing to make a change in his life and give himself time to recover emotionally, Wilson resigns from Princeton-Plainsboro. The team must push forward as they encounter a case involving an assistant to a high-profile executive, who is a textbook "Type A" personality.

When several people die suddenly and without warning five years after receiving transplants from a single organ donor, House and the team rush to save the only two surviving recipients. House has hired Lucas Douglas, a private investigator, to dig up information about the deceased despite the team's skepticism. Meanwhile, House auditions new best friends to replace Wilson, and soon uses Lucas for his own personal means to spy on Wilson and the other team members.

House and the team take on the case of a struggling artist who has been painting bizarre portraits. His undiagnosed illness is distorting his perception, threatening to undermine his career, his relationships and everything else in his life. House continues to have a private investigator dig up dirt on everyone on his team.

When House receives word that his father has passed away, he brushes off the news and dismisses the idea of going to the funeral. However, he is soon coerced into going despite his strongest protests. Back at Princeton-Plainsboro, the team encounters the case of a young woman adopted by American parents who collapsed while in China looking for her birth parents.

When a woman with whom Thirteen had a one-night stand falls ill and has a seizure at Thirteen's apartment after a night of partying, Thirteen accompanies the woman to Princeton-Plainsboro where House and the team take on her case. Meanwhile, House keeps his private investigator, Lucas hot on Wilson's trail.

The team takes on the case of a dreary middle-aged man who has been experiencing unexplained recurring blackouts and time lapses. Meanwhile, House finds out Cuddy is going to adopt a baby that is due in two weeks.

When an agoraphobic man falls mysteriously ill and adamantly refuses to leave his home to get treatment at the hospital, House and the team go to him to figure out what might be wrong.

The team takes on the case of a 16-year-old factory manager who fell ill when her lungs suddenly filled with fluid while at work. Meanwhile, Foreman asks for House's permission to work on a clinical trial and House rejects his proposal. In an effort to prove himself capable of working without House's supervision, Foreman takes on his own pediatric case. But when the unexplained illness brings the child to the brink of death, Foreman is left questioning his ability to work free from House's custody.

A gun-wielding man from the waiting room at the Princeton-Plainsboro clinic takes House, Thirteen and several patients from the waiting room hostage in Cuddy's office. The man claims to be sick with a long undiagnosed illness and demands medical attention from the best doctor in the hospital, threatening to kill any hostages necessary along the way.

House and the team take on the case of a high-profile fitness trainer who collapses while shooting an infomercial. Meanwhile, Thirteen begins her participation in a clinical drug trial for Huntington's disease led by Foreman, Kutner sets up and runs an online medical advice clinic under House's name and Cuddy moves into House's office while hers is being repaired, much to the dismay of her new officemate.

House and the team encounter a teenager who collapsed during her high school Christmas program. Foreman continues to work with Thirteen on the Huntington's disease drug trial, and their relationship progresses when he learns a valuable lesson from her. House gives a clinic patient an unbelievable holiday gift and keeps the team guessing about who may have sent him a particularly thoughtful Christmas present. Meanwhile, Cuddy receives an unexpected gift of her own.

At Cameron's urging, House and the team take on the case of a man living with such severe chronic pain that he tries to kill himself, unable to go on after living for years without a diagnosis or any relief from his suffering. Meanwhile, Foreman and Thirteen explore their now complicated relationship as they work together on the Huntington's disease clinical drug trial, and Cuddy finds that taking care of her newly adopted baby leaves her little time to run a hospital and baby-sit House at the same time.

Cuddy decides to spend more time at home to take care of her newly adopted baby and passes some of her day-to-day responsibilities off to Cameron, including supervising House. Cameron is forced to play House's games and becomes involved in a power struggle as he and the team take on the case of a Special Education teacher who collapsed after spitting up blood in the middle of class.

House and the team take on the case of a woman who collapsed in the middle of a cooking class, and they soon learn she is a highly-renowned cancer researcher who recently gave up her entire career in order to pursue her own personal happiness. As the patient's condition continues to worsen, so does Thirteen's as she begins to suffer serious and life-threatening reactions to the experimental Huntington's Disease clinical trial.

When a priest who runs a homeless shelter sees a bleeding Jesus hovering at his doorstep, he is admitted to the ER. House takes on the case as a distraction for the team while he confronts Foreman and Thirteen about their relationship.

The team encounters a teenage boy who collapsed from severe pelvic pain after playing basketball. Tests reveal the boy has genetic mosaicism, or both male and female DNA, and the boy's parents inform House and the team that the boy is unaware of his condition.

House and the team take on the case of Nick, a book editor who loses his inhibition and starts insulting coworkers at a dinner party one night before falling ill. Meanwhile, House suspects Wilson and Taub are keeping something from him when he catches them both in a lie. House is determined to get to the bottom of it.

House and the team take on the case of Morgan who works in a nursing home with a pet cat who only sleeps next to people if they are about to die - and does so with alarmingly accuracy. When it seems the cat has predicted her own death, Morgan, convinced she is about to die, fakes a seizure in order to get to House to have him diagnose her before it's too late.

We find ourselves inside the mind of Lee as he awakens after a bicycle accident in New York unable to move or communicate verbally. From his unique perspective, we hear Lee's inner thoughts as House, injured in a motorcycle accident, occupies the hospital bed next to him. Meanwhile, Wilson suspects House is hiding something from him when he refuses to divulge why he was in New York when he got into his motorcycle accident.

Charlotte, an older woman who has spent the last six months taking care of her husband Eddie, is rushed to Princeton Plainsboro for immediate treatment after collapsing from respiratory failure at Eddie's deathbed. With both in the hospital, the husband and wife team becomes a double mystery when Eddie's condition sporadically improves while Charlotte's condition deteriorates. Dr. Lawrence Kutner dies of suicide using a gun without any explanation why. While most of the cast grieve, House tries in vain to understand why Kutner died. 

Cameron postpones her vacation with Chase in order to ask House to accept the case of an environmental radical who collapsed at a protest with unexplainable symptoms. Although suspicious of her motives, House agrees. Meanwhile, House is unsure of Wilson's new healthy diet.

The team takes on the case of a deaf 14-year-old named Seth who collapsed after he started "hearing" explosions while competing in a wrestling match. Meanwhile, House's lack of sleep starts to play tricks on his mind, but he finds his insomnia may be a gift instead of a burden.

House and the team take on the case of a ballerina whose lungs collapse in the middle of a performance. When the treatment causes her skin to fall off, the dancer faces not only the prospect of never dancing again but also of dying an agonizing death. Meanwhile, House continues to suffer from a severe lack of sleep and is still haunted by Amber. While enlisting Wilson's help to diagnose himself, he is willing to do the unthinkable to make his visions stop.

House and the team are intrigued by Scott, a man whose left brain and right brain operate independently, leaving him with two distinct personalities and no control over some of his actions. Cameron and Chase get married. House admits himself to a detox program.

House begins a detox program at Mayfield Psychiatric Hospital to get the Vicodin out of his system in an attempt to control his hallucinations.

House returns home to Princeton, where he continues to focus on his recovery but surprises Cuddy with the news that he's making a big change in his life. He's resigning. Meanwhile, the team cannot diagnose a loud-mouthed video game creator who posts each new symptom on the internet and opts for treatments suggested by the online community rather than by the doctors. Foreman angles for House's job, but the pressure to solve the case creates tension in his relationship with Thirteen. Taub quits when he learns that House isn't returning and begins searching for a new job.

When a controversial African politician (guest star Jones) falls ill, he is brought to Princeton Plainsboro for treatment. The team struggles with whether to help a merciless dictator being subpoenaed for crimes against humanity in his country. Meanwhile, Wilson tries to make peace with a feuding neighbor, but House's prying exacerbates the problem.

A wealthy businessman brings his teenage son, who is suffering from inexplicable stomach pains, to Princeton Plainsboro and insists on having Dr. House handle the case. Meanwhile, Foreman and Chase prepare to present information on the Dibala case.

The team takes on the case of a reckless police detective who has a family history of sudden heart failure that killed his father, grandfather and great-grandfather all at age 40. Meanwhile, Chase is haunted by his actions in the Dibala case, and House confronts some ghosts of his own.

After a wild night out, a teenage girl is brought to Princeton Plainsboro with severely swollen appendages. Meanwhile, Cuddy and Wilson attend a medical conference for pharmacology and public policy. House tags along, planning to use the outing as an opportunity to push a personal agenda, but things don't go as expected.

After House's medical license is reinstated, he reclaims his role as Head of Diagnostics in time to treat Hank Hardwick, an adult film star admitted to Princeton Plainsboro for pulsating eye pain. Meanwhile, Cuddy is reminded that the hospital is not conducive to healthy personal relationships, and House angles to form a dream team.

On the eve of Thanksgiving, House and the team treat James Sidas, an exceptionally brilliant physicist and author who traded his successful career for a job as a courier. A myriad of strange symptoms nearly stumps the doctors. Also, they wrestle with strained personal relationships. Cameron left Chase to live in Chicago.

When an old friend and former patient of Wilson's exhibits paralysis in his right arm, Wilson puts himself on the case. House wagers Wilson that the patient's symptoms are attributed to new cancer cells. Wilson accepts even though he is reluctant to believe cancer has returned. Cuddy continues her search for real estate.

When drug dealer Mickey mysteriously collapses while negotiating a sale, his partner-in-crime, Eddie, accompanies him to Princeton Plainsboro for treatment. But with a major deal pending, Mickey is not forthcoming with the necessary personal information the team needs to treat him. House and Wilson compete for a new neighbor's affection. Chase, Thirteen, and Taub play a practical joke.

The team takes on the case of Valerie, an attractive female executive experiencing random episodes of excruciating pain. Meanwhile, House uncharacteristically attempts to alleviate his conscience by reaching out to a former medical school colleague he wronged.

House and the team rush to treat an ailing college football star in time for the patient to compete in NFL tryouts. But when the patient experiences an onslaught of varied and unusual symptoms, the team has trouble reaching a consensus on how to effectively treat him in time. Meanwhile, Foreman's brother Marcus makes a surprise visit to the hospital.

During a day in the life of Princeton Plainsboro's Dean of Medicine, Dr. Lisa Cuddy, the inner workings of the hospital are seen through her eyes. This day proves to be especially trying as Cuddy wrestles with myriad hospital issues and staff disputes that test her perseverance and skills as an administrator, all while juggling issues in her personal life.

House and the team take on the case of an avid blogger admitted with sudden bruising and bleeding. From her hospital bed, the patient blogs about her symptoms, doctors, and prospective diagnoses to her dedicated band of followers and solicits their advice on a course of treatment. Wilson and House discover secrets about each other.

The team takes on the case of a high school senior who inexplicably blacks out during a class field trip and repeatedly hallucinates. Meanwhile, Taub airs his dirty laundry at work, and Wilson attempts to furnish his condo.

Princeton Plainsboro goes on lockdown when a newborn disappears from the nursery, preventing anyone from entering, leaving, or moving within the hospital. While House and his team members are trapped in various parts of the building, new insights surface about the team's personal lives, relationships, and regrets. Chase and Cameron finalize their divorce. 

House and the team take the case of Sir William, a knight from a community of men and women living according to the ideals of the High Renaissance. As the team searches the medieval village for environmental factors contributing to Sir William's rapidly deteriorating health, Thirteen and Sir William debate the acts that define honor and loyalty. Meanwhile, Wilson starts dating his ex-wife, Sam.

House and the team take the case of a woman named Julia, who is in an open marriage and  suddenly becomes ill during a date with her on-the-side boyfriend. Meanwhile, House tests Wilson's relationship with Sam.

The team takes on the case of an ailing groom-to-be who harbors undisclosed secrets from a previous relationship. As his fiancée tries to get answers to her many questions, a frustrated team winnows down the possibilities. Meanwhile, House spends extra-curricular time with his Princeton Plainsboro colleagues at Wilson's insistence, performing a karaoke rendition of a Gladys Knight & The Pips classic with Foreman and Chase during a raucous night out.

During a session with Dr. Nolan, House recounts the case of a woman who arrives at the Princeton Plainsboro emergency room with an unexplained illness and no recollection of who she is. While trying to solve the mystery of the woman's condition, House must also help her piece together her identity. 

Cuddy, House and members of the team join forces with a search-and-rescue team to provide much-needed medical attention at the scene of an emergency.

House and Cuddy explore the ramifications of their feelings and attempt to make a real relationship work. Meanwhile, Princeton Plainsboro is left without a neurosurgeon on-site due to a colleague's illness, threatening the hospital's accreditation as a Level 1 Trauma Center. As the team attempts treatment to get their sick colleague back to work, they discover there is more to the illness than they initially suspected and turn to House for direction. Instead, House remains elusive, leaving the team on its own.

When Della, a seemingly healthy and active 14-year-old, suddenly collapses during a skateboarding exhibition, House and his team struggle to diagnose her condition and reassure her parents, who already have to cope with their son's terminal illness. House and Cuddy face the challenge of handling their romantic relationship at work.

Alice, the author of a popular children's book series, inexplicably suffers a seizure moments before she attempts to take her own life. The Princeton Plainsboro team faces the challenges of evaluating her underlying medical conditions and unstable psychological state. House, a fan of the books, puts her on psych hold but deals with a patient more eager to die rather than be cured. Meanwhile, House worries that he will lose Cuddy because they have nothing in common. House and Cuddy double-date with Wilson and his ex-wife Sam.

Princeton Plainsboro admits a patient named Margaret McPherson suffering severe and uncontrollable vomiting. House and the team make unexpected discoveries about her identity as they assess her symptoms. Meanwhile, a visit from House's massage therapist forces House and Cuddy to confront the reservations in their relationship. Also, House tasks Chase with hiring a replacement for Hadley; he hires Dr. Kelly Benedict who later quits. 

After a newborn experiences inexplicable breathing problems and liver failure, House and the team look at the baby's mother, Abbey's, own medical history for possible clues. Meanwhile, following Cuddy's directive, House challenges Foreman and Taub to hire a female doctor to join the team. When Cuddy asks House to babysit her daughter, both House and Wilson learn a few hard lessons in parenting.

It's election season, and in the midst of a tight campaign, an incumbent New Jersey senator's campaign manager falls ill with liver failure and temporary paralysis. Cuddy pushes House to add a female doctor to his team by hiring brilliant third-year medical student Martha Masters in Thirteen's absence.

After a 200-year-old medicine jar found on an off-shore shipwreck shatters in a teenage girl's palm, she is admitted to Princeton Plainsboro for symptoms closely linked to smallpox. Meanwhile, Wilson and Sam comfort a 6-year-old chemotherapy patient, who prompts them to examine their relationship. House makes a dangerous decision that puts his life in jeopardy. 

Science and faith are called into question when a patient is admitted to the hospital after he starts coughing up blood while being crucified. Meanwhile, Taub questions his wife Rachel about her relationship with an infidelity support group member and the team attends a co-worker's wedding where Wilson's relationship with Sam takes an unexpected turn.

When a man puts his life on the line to save a stranger who fell onto the subway tracks, he emerges from the dramatic scene miraculously unscathed but then suddenly collapses. Meanwhile, House tries to avoid Cuddy's birthday dinner with her opinionated mother, Arlene, and Taub draws unexpected attention when his face graces billboards advertising the hospital.

A teenage military trainee at a juvenile offender training camp suffers peculiar symptoms after enduring an intense training course, and mysteriously, his drill sergeant is soon admitted for similar symptoms. Sensing Cuddy's stress over her daughter Rachel's enrollment at a prestigious preschool, House secretly prepares Rachel for observations and reveals a soft spot for the toddler.

After complaining about unusual symptoms, Cuddy's mother, Arlene, is admitted to Princeton Plainsboro. Still, stubborn Arlene insists that House be removed from the case, forcing House to develop non-conventional - and illegal - means to treat his patient.

When a waitress with a perfect memory suffers temporary paralysis, her older sister visits her in the hospital, which triggers high stress levels and even more health complications. Meanwhile, Foreman volunteers to help Taub prepare for a medical examination, and House, determined to help Wilson get back in the dating scene, discovers Wilson's secret new companion.

House participates in a school's Career Day and breaks a few rules by sharing explicit medical stories. Waiting outside the principal's office, he meets two fifth-grade students who assess House's relationship woes and try to help him understand how his selfish antics prevent him from showing Cuddy how he really feels.

After breaking out in a severe rash triggered by caustic chemical exposure at his blue-collar job, a patient is admitted. As the team treats him, they discover that he has led his wife to believe he is still maintaining his once-lucrative real estate career. Meanwhile, Cuddy is honored with an award and needs House to be at the charity event for support. But his attendance is threatened when his patient's battle to survive forces him to question his practice and happiness. Chase and Masters teach each other a lesson in forging meaningful personal and professional relationships.

Tension reaches new heights when Cuddy faces sobering news that forces her to reevaluate her priorities. While House is distracted by his concern for Cuddy's well-being, the team treats a teenage patient whose worsening symptoms and suspicious body scars indicate more than just physical illness. Sensing the teen's troubled emotional and mental state, Taub turns to the patient's personal life for clues and uncovers disturbing home videos that could put the lives of his peers in danger. Meanwhile, Cuddy remains hopeful that House will be fully present when she needs him most, and a series of dreams, including a musical scene choreographed by Mia Michaels, provide glimpses into her life and her relationship with House.

The team treats a professional bull rider after a bull attacks him. The team must determine the causes behind the patient's disappearing symptoms and seizures, concluding he needs risky open-heart surgery. The team enlists House's advice from outside the hospital as he attends to issues unrelated to the case. Meanwhile, Masters develops a crush on the patient, surprising Taub.

A young homeless man who is a former drug addict is found in a park showing signs of olfactory impairment and horrific scars and burn marks on his chest. With an uncertain identity and the patient's severely worsening conditions, the team looks to the patient's records and family history to understand his detachment. Meanwhile, Cuddy reveals her guilt to Wilson about breaking up with House.

House discovers that Thirteen has been in prison and meets her when released. He has a dual purpose for being there: he wants to know what she did to end up in jail, and he needs her help to win a local spud-gun shooting contest. Meanwhile, the team treats a science teacher suffering from severe respiratory illness. Taub tries to get back into the dating scene but retreats to his old habits.

Masters faces a career crossroads on her last day as a medical student and struggles with the choice to continue on the path to become a surgeon or to accept the rare opportunity to join House's team officially. Meanwhile, the team treats a 16-year-old girl who inexplicably collapsed days before embarking on an ambitious sailing tour around the globe. Despite the patient's life-changing diagnosis, the patient's family insists on getting her back on the seas in time for her potentially record-breaking launch. But to the team's surprise, including House, Masters makes a bold decision regarding the patient's treatment.

After suffering partial paralysis while searching for a long-lost love, lottery winner Cyrus Harry arrives at Princeton Plainsboro for treatment by House and the team. The patient also suffers from multiple types of cancer. The team must figure out if his new millionaire lifestyle is making him sick. Meanwhile, Cuddy's mother, Arlene, threatens to sue the hospital for malpractice over her treatment, jeopardizing both Cuddy's and House's medical licenses. Foreman and Chase make a bet over who is repressing the uglier side of their personality more.

After losing a bet with Wilson over a boxing match, House believes his fighter has an underlying medical condition that cost him the fight. House presses the boxer for more information to prove his case and attempts to breathe new life into the losing fighter's career. Meanwhile, he leaves his team alone to help a bomb scientist who suffered a seizure. They also suspect House may be experimenting with a new drug to relieve his leg pain.

When House discovers that the experimental drug he's been using causes fatal tumors, he decides to attempt to excise them himself. However, he can't complete the surgery and needs Cuddy's help. Meanwhile, Thirteen's friend from prison and relapsed drug user, Darrien, arrives at her apartment unannounced, needing medical care after being stabbed. With her friend unwilling to go to the hospital, Thirteen enlists Chase's assistance when the friend loses sensation and movement in her arm. Also, Taub receives some unexpected news that could change his life.

The team treats a performance artist Afsoun Hamidi who deliberately made herself ill, to turn the diagnostics department into her new masterpiece documentary. House must decide which of her symptoms are real and which are self-inflicted. The team questions whether treatments are necessary and if they are unwitting participants in creating a piece of her art. As the case progresses, House vows to change his life but remains rooted in old habits. After the case is over, House finally deals with his anger over the breakup and lashes out by driving through Cuddy's dining room and escaping to a beach.

House spent the last year in prison at the East New Jersey Correctional Facility after ramming his car into Cuddy's house and attempting to escape responsibility with his trip outside the country. Entirely cut off from his old life, House determines his current problems result from his inability to deal with people. Feeling he will never be able to practice medicine again, he plans instead to return to university to earn a doctorate in physics. This field will all but assure his isolation from other human beings. When a fellow inmate becomes ill with strange symptoms, House tries to help him while encouraging the young prison clinic doctor, Jessica Adams, to risk her job and trust his diagnosis.

A surprising visitor, Foreman, makes House an offer he can't refuse for a conditional early release from prison. This offer allows House to help the Princeton Plainsboro team treat a unique patient to save the life of an organ recipient being treated by Wilson. Although House finds himself back on familiar ground, he quickly realizes that much has changed since he left, and he is forced to work on the case with smart yet timid resident Dr. Chi Park. After several inconclusive treatments and time running out, House and Dr. Park are left with one last option to examine the patient's medical history that could compromise House's conditional agreement with the hospital. Meanwhile, House makes an effort to reconnect with Wilson despite a cold reception.

House and Park treat a patient, Benjamin Byrd, who collapsed suddenly after making a surprisingly large charity donation. When the patient offers to donate an organ to another patient, the doctors must convince Dr. Adams to help them confirm whether Benjamin is in his right mind or not. They are convinced his extreme altruistic behavior is a symptom of a deeper medical disorder. Feelings of guilt hamper thirteen's pursuit of happiness.

A CEO falls mysteriously ill just days before he signs a contract that would relocate his company's entire labor force to China. House attempts to make an underhanded business transaction with his wealthy patient, but when his condition worsens, the team must work around the clock to save his life. Meanwhile, Park prepares for her hearing with the Princeton Plainsboro Disciplinary Committee chaired by Foreman, and Adams' outlook on her patient's business venture reveals her deeper feelings about loyalty.

A man well-respected in his community suddenly collapses, and in diagnosing his symptoms, the team discovers that the patient has been hiding dark and dishonest secrets about his personal and professional life. But when the patient openly confesses his wrongdoings to his family and community, he compromises his chances of receiving the proper medical treatment. Meanwhile, Chase and Taub rejoin the team, and Taub struggles to balance work and fatherhood. House will stop at nothing to manipulate Taub into taking a DNA test to prove he is the father of his two six-month-old daughters.

A teenage boy attempting to follow in his late father's footsteps as an entertainer is admitted to Princeton Plainsboro with partial paralysis. As the team searches for a bone marrow match, they uncover a disturbing family secret. Meanwhile, House looks for creative ways to remove his ankle monitor so that he can attend a boxing match in Atlantic City, and he treats a patient convinced he has diabetes. Also, Taub faces a tough decision when his ex-wife Rachel tells him that she wants to move across the country with their infant daughter.

The team learns that their 14-year-old patient is suffering from more than teen angst when her physical symptoms worsen. Despite Foreman's firm opposition, House becomes obsessed with solving a peculiar case of a deceased four-year-old patient, which gets him into serious trouble. Meanwhile, Park tries to get Chase to admit the reason behind his recent obsession with grooming.

A prosecutor suffers from what he believes to be cardiac arrest during an interrogation at the witness stand. The team's preliminary diagnosis is hyper-anxiety, but when Adams and Park investigate the patient's home and find a hidden arsenal of firearms, they uncover a more alarming and deep-seated psychological disorder. Wilson becomes obsessed with proving that House is hiding something in his home, Park slowly comes out of her social shell, and Foreman's lack of romantic relationships piques the interest of Taub and Chase. 

An Alzheimer's patient visits Princeton Plainsboro as part of a hospital-sanctioned drug trial. When he inexplicably suffers violent blood vomiting and an increasingly explosive temper, the team unravels a deeper marriage conflict between the patient and his dutiful wife. Meanwhile, when Wilson tells House about a patient who has never had sex with her husband of 10 years, claiming A-sexuality, House makes a wager that there has to be an underlying cause. Also, House and Foreman butt heads.

The team treats an underage and homeless female patient. When her symptoms worsen and call for an invasive surgery requiring adult consent, House and Adams argue over whether they should contact social services. Meanwhile, Taub has difficulty connecting with his infant daughters, and House threatens to exploit Foreman's relationship with a married woman.   

When a violent incident involving a patient has serious consequences for one staff member, House and the team are placed under review by Dr. Walter Cofield, Foreman's former mentor and current Chief of Neurology. As House and each member of his team recount the details of the dramatic and life-threatening incident, Cofield must weigh the team's unconventional brand of collaboration against their ability to save lives.

Chase takes on a patient, Moira, who is a cloistered nun on the verge of making her life-changing vows, and through the treatment process, he and Moira form a unique connection that tests their faith and reason. Meanwhile, House and Taub try to remain one step ahead of each other's pranks.

A marriage counselor collapses during a speaking engagement. But when put under close evaluation, the team notices behavioral changes that conflict with his motivational message on the roles of men and women. Meanwhile, House and his Ukrainian green-card "wife," Dominika, make a deal to convince Immigration that they are a happily married couple. This leads to a crash course where both learn something about love and marriage. House chooses Taub as the new team leader.

House and the team battle to save a successful, independent blind man who is struck down by a mysterious illness just before he asks for his girlfriend's hand in marriage. Meanwhile, House's mother unexpectedly arrives at Princeton Plainsboro to inform him of her new beau.

The team treats an Army veteran charged with treason after leaking classified information. But the patient's life is put at risk when he refuses treatment unless he and his brother receive information about their late father, a war veteran, which raises questions about loyalty to one's family and country. Meanwhile, Adams suspects House may be sick, so she recruits Wilson and the other team members to plan an intervention and investigate his illness.

House and the team take on the case of a 22-year-old minor league hockey player who collapsed while coughing up blood after a fight on the ice. Meanwhile, House drops a bomb on Wilson that he has an eleven-year-old son. Chase offers to help Park change her living arrangement and become his roommate.  

House and the team take on the case of a man who starts tearing blood. Meanwhile, House is interviewing for a new favorite hooker since his current favorite, Emily has decided to get married and leave the business. Desperate for Emily's "companionship," House teams up with his "wife" Dominika to sabotage Emily's budding relationship.

House and the team take on the case of a young Hmong boy who has violent dreams of being choked and then wakes up but is still unable to breathe. Meanwhile, Park has intimate dreams involving co-workers, which causes the team to question whether or not there's significance to what each of them dreams. Dominika discovers House has kept secret that she received her American citizenship and is free to leave him. So, she does. Wilson has cancer and tells House.

When the team takes on the case of Emily, a six-year-old girl with multiple health issues, they must collaborate with her mother, Elizabeth, who is also a doctor specializing in Emily's condition. Meanwhile, House and Wilson take a little vacation to treat Wilson's cancer in House's apartment.

Over his years performing autopsies at Princeton-Plainsboro Teaching Hospital, Dr. Peter Treiber often identifies mistakes made by physicians that caused the patient's death. These observations make him question the skills of nearly all the doctors on staff, all that is, except House. When he falls ill, he demands that only House make medical decisions concerning his care. Unfortunately, House and Wilson have taken off on an impromptu road trip without telling anyone, leaving the team to figure out how to treat Treiber while making him believe that House is calling all the shots. Lastly, Chase decides to step out of House's shadow and leave the hospital.

The team takes on the case of Derrick, a 19-year-old college student who had a mysterious nosebleed during cheerleading practice, and discovers that his health issues are likely both physiological and psychological. Possibly suffering from schizophrenia, Derrick claims to hear his deceased brother's voice in his head. Meanwhile, Foreman tries a different approach with House. Wilson and House continue to come to terms with Wilson's cancer.

Facing a 6-month jail term and realizing that he won't be there for Wilson at the end, House finds himself examining his entire life while contemplating a dismal future without his best friend. Trapped in a burning building, House must come to terms with his life, choices, personal demons, and future.